Piroctone Olamine Powder
Piroctone olamine is an active ingredient commonly used in personal care and cosmetic products, particularly those designed for scalp and skin health. Below is an introduction to its key characteristics and applications:
General Information
- Chemical Name: Piroctone Olamine
- Chemical Formula: C16H30N2O3
- CAS Number: 68890-66-4
- Molecular Weight: 298.43 g/mol
- Appearance: White to off-white crystalline powder
- Odor: Odorless or slight characteristic odor
Properties
- Solubility:
- Soluble in ethanol and propylene glycol
- Slightly soluble in water
- pH Range: 7.5 - 9.0 (1% aqueous solution)
- Melting Point: 130 - 135°C
- Stability: Stable under recommended storage conditions.
- Storage Conditions:
- Store in a cool, dry place.
- Keep away from direct sunlight and heat sources.
Applications
- Primary Uses:
- Antifungal and antimicrobial agent in personal care products.
- Commonly used in shampoos, conditioners, and other hair care formulations to control dandruff and scalp issues.
- Mechanism of Action:
- Inhibits fungal growth, specifically Malassezia spp., which contributes to dandruff and seborrheic dermatitis.
Chemical Composition:
Piroctone olamine, a compound derived from hydroxamic acid, is a pyridine derivative. Its structure combines antifungal and antibacterial properties with excellent solubility, making it suitable for various formulations.
Appearance:
Typically presented as a white to off-white crystalline powder, piroctone olamine is odorless or has a faint characteristic scent.
Solubility:
It is moderately soluble in water and more soluble in alcohol and glycols, allowing for versatility in product formulations.
Mechanism of Action:
Piroctone olamine functions by disrupting the cell membrane of fungi and certain bacteria. It is particularly effective against Malassezia species, which are often implicated in dandruff and seborrheic dermatitis.
Applications
- Anti-Dandruff Products
- Found in shampoos, conditioners, and scalp treatments to combat flaking and itching caused by dandruff.
- Skin Care
- Used in creams, lotions, and gels to treat fungal skin conditions and maintain healthy skin.
- Preservative Agent
- Its antimicrobial properties make it useful as a preservative in cosmetic and personal care formulations.
Advantages:
- Broad-spectrum antimicrobial efficacy.
- Gentle on the skin and scalp, making it suitable for daily use.
- Helps reduce scalp inflammation and improve overall hair health.
Usage Guidelines
- Concentration: Commonly used at levels between 0.1% and 1% depending on the formulation and intended application.
- Compatibility: Stable across a wide pH range (4–9) and compatible with other active ingredients.
Safety and Regulations
Piroctone olamine is considered safe for use in cosmetic products when formulated within recommended concentrations. Its mild profile makes it a preferred choice for sensitive skin and scalp conditions.
Packaging
- Available in sealed containers to prevent moisture and contamination.
Shelf Life
- Typically 24 months when stored properly.
Piroctone olamine, commonly used in anti-dandruff shampoos and skincare products, is considered safe when used as directed. However, like many chemical compounds, it can cause side effects in some individuals. Here are potential side effects or warnings to consider when using products containing piroctone olamine:
Potential Side Effects:
- Skin Irritation:
- Redness, itching, or mild irritation may occur, especially in people with sensitive skin.
- Allergic Reaction:
- Rarely, it may cause an allergic reaction. Symptoms include hives, rash, swelling, or difficulty breathing. If these occur, discontinue use and seek medical attention.
- Eye Irritation:
- If the product comes into contact with your eyes, it may cause temporary stinging or discomfort. Rinse thoroughly with water.
- Dryness or Flaking:
- Overuse or frequent application may result in excessive dryness or flaking of the scalp or skin.
- Interaction with Other Products:
- May interact with other active ingredients in skincare or haircare products, potentially reducing its efficacy or increasing irritation.
Warnings:
- Patch Test: Always perform a patch test before using a new product to ensure you do not have an adverse reaction.
- Use as Directed: Follow the instructions provided on the product label. Overuse may lead to increased side effects.
- Pregnancy and Breastfeeding: Consult a healthcare provider if you are pregnant or breastfeeding before using products containing piroctone olamine.
- Children: Keep out of reach of children and avoid use on children unless directed by a healthcare professional.